Find coaches from San Francisco, US to St. Louis

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Today28 Aug
Tomorrow29 Aug
from US$167
Sat30 Aug
Sun31 Aug
Mon1 Sept
Tue2 Sept
Wed3 Sept
Thu4 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 29 August at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: 31 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 29 August at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: 31 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: 31 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: 31 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: 1 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Francisco, US to St. Louis: Trip Overview

Average ticket priceUS$185
Average bus trip duration2d 6h
Number of daily buses6
Earliest bus departure07:45
Distance1736 miles
Latest bus departure23:25

San Francisco to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from San Francisco to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Francisco to St. Louis.

Discover how much the bus trip from San Francisco to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Francisco, US - St. Louis

  1. How far is St. Louis from San Francisco by coach?

    The distance between San Francisco and St. Louis by coach is approximately 1740 miles (2806 km).

  2. Is there a way to reach St. Louis from San Francisco without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/08
No data
27/08
US$127
Today
No data
29/08
US$170
30/08
No data
31/08
No data
01/09
No data
02/09
No data
busbud logoThe cheapest trip from San Francisco, US to St. Louis was searched and found on 27 Aug 2025 with a price of US$127

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to St. Louis as early as possible.

You can expect to pay from US$127 to US$177 for a bus ticket from San Francisco, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$170, which is on 2025-08-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Francisco to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Francisco to St. Louis.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Francisco to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Francisco to St. Louis.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to San Francisco, US by bus?

Bus from St. Louis to San Francisco, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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