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Compare 2 ways to go from Portland to Greenville.
Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 1 hour 35 minutes and with fares starting at just $214, it presents an excellent value for a comfortable ride.
Bus Portland, ME to Greenville, SC: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Portland to Greenville Bus
Busbud helps you find a bus from Portland to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Portland to Greenville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Portland to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Portland and Greenville?
Frequently asked questions for your trip Portland, ME - Greenville, SC
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Portland and Greenville!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Portland to Greenville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to Greenville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Portland to Greenville.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Portland, ME to Greenville, SC?
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Portland
Buses Leaving from Portland
- Bus from Portland to San Francisco
- Bus Portland - Denver
- Portland - Boston
- Bus from Portland to Washington
- Bus Portland - Las Vegas
- Portland - Dallas
- Bus from Portland to New York City
- Bus Portland - Bangor
- Portland - Providence
- Bus from Portland to Orlando
- Bus Portland - Hartford
- Portland - Philadelphia
- Bus from Portland to New Haven
- Bus Portland - Waterville
- Portland - Newark
Buses Going to Portland
- Bus from Seattle to Portland
- Bus Boston - Portland
- Washington - Portland
- Bus from Denver to Portland
- Bus Chicago - Portland
- Medford - Portland
- Bus from New York City to Portland
- Bus Manchester - Portland
- Lewiston - Portland
- Bus from Bangor to Portland
- Bus Hartford - Portland
- Waterville - Portland
- Bus from Philadelphia to Portland
- Bus Newark - Portland
- Concord - Portland
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Bus Greenville - Spartanburg
- Greenville - Charleston
- Bus from Greenville to Greensboro
- Bus Greenville - Chicago
- Greenville - Miami
- Bus from Greenville to Atlanta
- Bus Greenville - Charlotte
- Greenville - New York City
- Bus from Greenville to Knoxville
- Bus Greenville - Tarboro
- Greenville - Anderson
- Bus from Greenville to Macon
- Bus Greenville - Orlando
- Greenville - Dallas
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Orlando - Greenville
- Bus from Charlotte to Greenville
- Bus Charleston - Greenville
- Anderson - Greenville
- Bus from Asheville to Greenville
- Bus New York City - Greenville
- LaGrange - Greenville
- Bus from Miami to Greenville
- Bus Fayetteville - Greenville
- Spartanburg - Greenville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- Houston - Austin
Popular airport transfers
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- Bus to Portland, ME
- Bus to Greenville, SC
- Portland, ME to Greenville, SC Buses