Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | UC Irvine (Crawford Hall) | Greyhound Station | Cheapest | ||||
 | Bus | Anaheim Regional Transportation Intermodal Center | Greyhound Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Santa Ana Bus Station | Greyhound Station | No tags | ||||
| Bus | Santa Ana Bus Station | Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Santa Ana Bus Station | Seattle–Tacoma Int'l Airport (SEA) | No tags |
Last refresh of the prices: Yesterday at 1:45 PM PST.
Get from Santa Ana to Seattle
The journey takes about 1 day, 4 hours 15 minutes and with fares starting at just $185, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Ana and Seattle?
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Stops in Seattle
- A503 S Royal Brougham Way, Seattle, WA 98134, USA
- C
Washington State Convention Center
705 Pike St, Seattle WA 98101, USA, , Pick-up is at the Charter Bus Loading Zone on 8th Avenue at the corner of 8th Ave. and Pike Street. - D2001 W Garfield St, Seattle WA 98119, USA
- E
Pier 66
2203 Alaskan Way, Seattle WA 98121, USA - F
International District
700-822 5th Ave S, Seattle, WA 98104, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Santa Ana, US to Seattle by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Ana to Seattle?
The cheapest bus tickets from Santa Ana to Seattle start from $185. The average price for this route is around $286. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Ana to Seattle?
The average bus trip duration from Santa Ana to Seattle is 1d 4h, covering a distance of 982 miles (1584 km). The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Santa Ana to Seattle route?
Several major train operators operate on this route with 6 trains available per day.
What is the earliest and latest departure time for the bus from Santa Ana to Seattle?
The earliest bus departs from Santa Ana to Seattle at 8:15am. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Santa Ana to Seattle?
A bus trip from Santa Ana to Seattle generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Ana, US to Seattle was searched and found on Nov 27, 2025 with a price of $223To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Seattle, as early as possible.
You can expect to pay from $223 to $406 for a bus ticket from Santa Ana, US to Seattle based on the last 2 days. You can expect to find the cheapest price for the trip at $401 which is on 2025-11-30.
