Bus Tickets from St. Louis to Philadelphia, PA

Find affordable bus tickets from St. Louis to Philadelphia, PA with flexible options. Book your trip now

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TodayJul 25
from $166
TomorrowJul 26
from $102
SunJul 27
from $114
MonJul 28
from $121
TueJul 29
from $104
WedJul 30
from $111
ThuJul 31
FriAug 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 26 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 27 at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 26 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 27 at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 27 at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 28 at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 27 at
    Destination city: Philadelphia
    Destination location: Philadelphia, 199 Spring Garden St
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from St. Louis to Philadelphia.

Bus
Average Price$97 - $308Average Duration1d 5h
33kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$162 - $460Average Duration1d 8h
118kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St. Louis to Philadelphia

Among the sustainable travel choices, the bus stands out as the good way to reach Philadelphia. The journey takes about 1 day, 5 hours 50 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.

15bus per day
1d 5hAverage Duration
$97Cheapest ticket
33kgCO₂ emissions

Bus St. Louis to Philadelphia, PA: Trip Overview

Average ticket price$129
Average bus trip duration1d 5h
Number of daily buses15
Earliest bus departure1:40am
Distance808 miles (1303 km)
Latest bus departure11:30pm

St. Louis to Philadelphia Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St. Louis to Philadelphia.

Bus service from St. Louis to Philadelphia will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from St. Louis to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip St. Louis - Philadelphia, PA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/23
$97
07/24
$136
Today
$158
07/26
$94
07/27
$106
07/28
$113
07/29
$103
07/30
$103
busbud logoThe cheapest trip from St. Louis to Philadelphia, PA was searched and found on Jul 26, 2025 with a price of $94

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Philadelphia, PA, as early as possible.

You can expect to pay from $94 to $291 for a bus ticket from St. Louis to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-07-26.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St. Louis to Philadelphia but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St. Louis to Philadelphia, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Philadelphia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Philadelphia while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St. Louis to Philadelphia, PA?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from St. Louis to Philadelphia, PA

You can also go to Philadelphia, PA by train

Train from St. Louis to Philadelphia, PA

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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