What is the distance between Syracuse and Pittsburgh?

The distance between the two cities is 268 miles (432 km).

What are the departure and arrival stations when taking the bus from Syracuse to Pittsburgh?

If you're headed to Pittsburgh from Syracuse, chances are that your bus will depart from Regional Transportation Center and arrive at Intermodal Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus Syracuse to Pittsburgh from $65 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Pittsburgh on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	9:25am	Syracuse (Regional Transportation Center)	14h 30m	11:55pm	Pittsburgh Intermodal Station	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	11h 40m	4:10pm	Pittsburgh Intermodal Station	Fastest
	Bus	7:30am	Syracuse (Regional Transportation Center)	14h 50m	10:20pm	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	3:55pm	Syracuse (Regional Transportation Center)	14h 35m	6:30am	Pittsburgh Intermodal Station	No tags
	Bus	9:00pm	Syracuse (Regional Transportation Center)	12h 50m	9:50am	Pittsburgh Intermodal Station	No tags

Last refresh of the prices: Today at 8:40 PM EST.

Get from Syracuse to Pittsburgh

This route is served by bus only

The journey takes about 14 hours 30 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.

4bus per day

14h 30mAverage Duration

268 milesDistance

11kgCO₂ emissions

Where are the popular stops in Syracuse and Pittsburgh?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Compare bus companies

Greyhound

3.5/587,397 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,454 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

New York Trailways

4/54,414 reviews

Staff4.6

Timeliness4.1

Cleanliness4.5

Wifi3.2

Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.

Adirondack Trailways

4/51,127 reviews

Staff4.6

Timeliness4.3

Cleanliness4.8

Wifi2.4

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Syracuse, US to Pittsburgh by bus

What is the distance between Syracuse and Pittsburgh?
What are the departure and arrival stations when taking the bus from Syracuse to Pittsburgh?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

$105

11/25

$152

Today

$173

11/27

$85

11/28

$138

11/29

$89

11/30

$145

12/01

$89

The cheapest trip from Syracuse, US to Pittsburgh was searched and found on Nov 27, 2025 with a price of $85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Pittsburgh, as early as possible.

You can expect to pay from $85 to $343 for a bus ticket from Syracuse, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $85 which is on 2025-11-27.