Bus Tickets from Columbus, OH to Des Moines

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TomorrowJul 20
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SatJul 26
from $143
SunJul 27

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 26 at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: July 27 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: July 27 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Columbus to Des Moines: Trip Overview

Average ticket price$176
Average bus trip duration1d 1h
Number of daily buses2
Earliest bus departure4:00am
Distance565 miles (911 km)
Latest bus departure2:30pm

Columbus to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Columbus to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Columbus to Des Moines will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Columbus, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Columbus, OH - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/17
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07/18
$159
Today
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07/20
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07/21
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07/22
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busbud logoThe cheapest trip from Columbus to Des Moines was searched and found on Jul 18, 2025 with a price of $159

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to Des Moines, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Columbus to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Columbus to Des Moines, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Columbus to Des Moines.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Columbus to Des Moines.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Columbus by bus?

Bus from Columbus to Des Moines

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