Bus Tickets from San Ysidro, CA to Louisville

Next departures

Next departures for San Ysidro to Louisville on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		San Ysidro Bus terminal
    		Louisville, KYCheapest
    Greyhound Lines, Inc.
      		San Ysidro Bus terminal
      		Louisville, KYFastest
      Greyhound Lines, Inc.
        		San Ysidro Bus terminal
        		Louisville, KYNo tags

        Last refresh of the prices: Yesterday at 9:47 AM PDT.

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        Get from San Ysidro to Louisville

        This route is served by bus only

        The journey takes about 2 days, 3 hours 30 minutes and with fares starting at just $167, it presents an excellent value for a comfortable ride.

        2bus per day
        2d 3hAverage Duration
        1792 milesDistance
        72kgCO₂ emissions

        Bus San Ysidro, CA to Louisville: Trip Overview

        Average ticket price$245
        Average bus trip duration2d 3h
        Number of daily buses2
        Earliest bus departure6:55am
        Distance1792 miles (2889 km)
        Latest bus departure7:00pm

        San Ysidro to Louisville Bus

        Busbud helps you find a bus from San Ysidro to Louisville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

        We make it our job to connect you with the most dependable bus companies that cover bus service from San Ysidro to Louisville.

        From cheap bus tickets to more luxurious buses traveling from San Ysidro to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

        Frequently asked questions for your trip San Ysidro, CA - Louisville

        Find cheapest prices for buses

        Price is for a one-way ticket for one passenger and based on past searches.

        Best price found
        10/31
        $221
        11/01
        $440
        Today
        $260
        11/03
        $238
        11/04
        $192
        11/05
        No data
        11/06
        $239
        11/07
        No data
        busbud logoThe cheapest trip from San Ysidro, CA to Louisville was searched and found on Nov 4, 2025 with a price of $192

        To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Louisville, as early as possible.

        You can expect to pay from $192 to $478 for a bus ticket from San Ysidro, CA to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $192 which is on 2025-11-04.

        About Bus Travel

        Bus Travel Tips

        Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Ysidro and Louisville!

        From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Ysidro to Louisville.

        Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Ysidro to Louisville that are otherwise impossible to come by with a plane.

        Tune out to the fine sounds of your best music playlist on your bus trip from San Ysidro to Louisville while indulging in miles on end of beautiful scenic views.

        Did you know?

        The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

        Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

        One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

        Will you be returning to San Ysidro, CA by bus?

        Bus from Louisville to San Ysidro, CA

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