Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Niagara Frontier Transportation Authority | Jacksonville Bus Station | CheapestFastest | ||||
 | Bus | Niagara Frontier Transportation Authority | Jacksonville Bus Station | No tags | ||||
| Bus | Buffalo (BUF) Airport | Jacksonville Bus Station | No tags |
Last refresh of the prices: Yesterday at 10:49 AM EDT.
Compare 2 ways to go from Buffalo to Jacksonville
Among the sustainable travel choices, the Bus stands out as a good way to reach Jacksonville. The journey takes about 1 day, 7 hours 55 minutes, and with fares starting at just $143, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Jacksonville?
Stops in Buffalo
- B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA - C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Jacksonville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Jacksonville?
The cheapest bus tickets from Buffalo to Jacksonville start from $143. The average price for this route is around $267. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Jacksonville?
The average bus travel time from Buffalo to Jacksonville is 1d 7h, covering a distance of 1422 km. The quickest bus can get you there in 1d 5h and is operated by FlixBus.
Which bus companies service the Buffalo to Jacksonville route?
What are the earliest and latest departure times for the bus from Buffalo to Jacksonville?
The earliest bus departs from Buffalo to Jacksonville at 5:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Jacksonville?
A bus trip from Buffalo to Jacksonville generates an estimated 35.545449999999995 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Buffalo to Jacksonville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12712 reviews.
Which bus company has the best Wi-Fi from Buffalo to Jacksonville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Buffalo to Jacksonville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Jacksonville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Jacksonville, FL was searched and found on Jun 13, 2026 with a price of $177To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Jacksonville, FL, as early as possible.
You can expect to pay from $177 to $365 for a bus ticket from Buffalo, NY to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $177 which is on 2026-06-13.
What's the cheapest way to go from Buffalo, NY to Jacksonville, FL?
The Bus is the cheapest travel choice for this destination
