Bus Tickets from Detroit (MI) to St Louis

Find affordable bus tickets from Detroit (MI) to St Louis with flexible options. Book your trip now

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TodayJun 13
from US$149
TomorrowJun 14
from US$107
SunJun 15
from US$86
MonJun 16
TueJun 17
from US$81
WedJun 18
from US$104
ThuJun 19
FriJun 20
from US$98

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 14 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 15 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 14 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 14 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 14 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 14 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 15 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 2:37 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Detroit to St Louis

Bus
Average PriceUS$69 - US$172Average Duration16h 55m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$80 - US$221Average Duration13h 41m
67kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Detroit to St Louis

Among the sustainable travel choices, the train stands out as a good way to reach St Louis. The journey takes about 13 hours 41 minutes, and with fares starting at just US$80, it presents an excellent value for a comfortable ride.

1.5333333333333332train per day
13h 41mAverage Duration
US$80Cheapest ticket
67kgCO₂ emissions

Bus Detroit to St Louis: Trip Overview

Average Ticket PriceUS$90
Average Bus Trip Duration16h 55m
Number of daily buses4
Earliest bus departure7:15am
Distance731 km
Latest bus departure11:25pm

Detroit to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Detroit to St Louis.

We make sure you can find a bus service from Detroit to St Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Detroit, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Detroit (MI) - St Louis

  1. How long does it take to get to St Louis from Detroit by bus?

    The typical travel time from Detroit to St Louis by bus is around 16h 55m. The fastest bus on this trip will get to St Louis in 12h 25m

  2. What is the distance between Detroit and St Louis?

    The distance covered from Detroit to St Louis is 733 km (454 miles).

  3. What are the departure and arrival locations for buses traveling from Detroit to St Louis?

    Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Gateway Station, in St Louis.

  4. What is the cheapest way to go from Detroit to St Louis?

    Taking the bus is the most budget-friendly option to travel from Detroit to St Louis. With a starting ticket price of US$69, this bus becomes your top pick for this journey.

  5. How much is the bus from Detroit to St Louis?

    The bus fare from Detroit to St Louis is approximately US$90.

  6. Is it possible to travel by overnight bus from Detroit to St Louis?

    Yes! Catch buses leaving from Detroit until 11:25pm and reaching St Louis on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-11
US$113
06-12
US$153
Today
US$141
06-14
US$99
06-15
US$78
06-16
US$64
06-17
US$73
06-18
US$96
busbud logoThe cheapest trip from Detroit to St Louis was searched and found on Jun 16, 2025 with a price of US$64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to St Louis, as early as possible.

You can expect to pay from US$64 to US$169 for a bus ticket from Detroit to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$64 which is on 2025-06-16.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Detroit to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to St Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to St Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Detroit to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Detroit by bus?

Bus from Detroit to St Louis

You can also go to St Louis by train

Train from Detroit to St Louis

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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