Bus Tickets from St Louis to San Antonio (TX), US

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TodayMay 31
TomorrowJun 1
from US$137
MonJun 2
TueJun 3
from US$153
WedJun 4
ThuJun 5
FriJun 6
SatJun 7

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 2 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Valley Transit
    FlixBus + Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:
  • Departure time: June 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 1 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: June 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 2 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Valley Transit
    Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:
  • Departure time: June 1 at
    Departure city: St Louis
    Departure location: St Louis, MO
    Arrival time: June 3 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 10:17 AM CDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from St Louis to San Antonio

Bus
Average PriceUS$80 - US$291Average Duration22h 15m
32kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$113 - US$222Average Duration1d 2h
116kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to San Antonio

Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 22 hours 15 minutes, and with fares starting at just US$80, it presents an excellent value for a comfortable ride.

3bus per day
22h 15mAverage Duration
US$80Cheapest ticket
32kgCO₂ emissions

Bus St Louis to San Antonio: Trip Overview

Average Ticket PriceUS$121
Average Bus Trip Duration22h 15m
Number of daily buses3
Earliest bus departure1:35am
Distance1275 km
Latest bus departure4:30pm

St Louis to San Antonio Bus

With Busbud, comparing and booking tickets for a bus from St Louis to San Antonio is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from St Louis to San Antonio will be provided by the most trusted bus companies.

Discover how much the bus trip from St Louis to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip St Louis - San Antonio (TX), US

  1. How long does it take to get to San Antonio from St Louis by bus?

    The typical travel time from St Louis to San Antonio by bus is around 22h 15m. For the shortest travel time, select the fastest bus available, which will take you to San Antonio in about 20h 40m.

  2. What is the distance between St Louis and San Antonio?

    The distance covered from St Louis to San Antonio is 1278 km (793 miles).

  3. What are the departure and arrival locations for buses traveling from St Louis to San Antonio?

    Buses traveling this route start their trip at Gateway Station, in St Louis, and end it at San Antonio Bus Station, in San Antonio.

  4. What is the cheapest way to go from St Louis to San Antonio?

    The least expensive option to go from St Louis to San Antonio would be going by bus. Starting at US$80, this bus is the most cost-effective option for your journey.

  5. How much is the bus from St Louis to San Antonio?

    The bus fare from St Louis to San Antonio is approximately US$121.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-29
No data
05-30
No data
Today
No data
06-01
US$170
06-02
No data
06-03
No data
06-04
No data
06-05
No data
busbud logoThe cheapest trip from St Louis to San Antonio was searched and found on Jun 1, 2025 with a price of US$170

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to San Antonio, as early as possible.

You can expect to pay from US$170 to US$170 for a bus ticket from St Louis to San Antonio based on the last 2 days. You can expect to find the cheapest price for the trip at US$170 which is on 2025-06-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St Louis to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from St Louis to San Antonio, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from St Louis to San Antonio will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St Louis to San Antonio.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from St Louis to San Antonio?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to San Antonio

You can also go to San Antonio by train

Train from St Louis to San Antonio

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