Find coaches from Boston, MA, US to Greenville, SC

Previously seen journeys

Next departures from Boston to Greenville on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Boston (South Station)
1116 Woodruff RdNo tags
FlixBus
151 Steel Pl, Cambridge
1116 Woodruff RdNo tags
Greyhound + FlixBus
Boston (South Station)
1116 Woodruff RdNo tags
FlixBus + Greyhound
Boston (South Station)
1116 Woodruff RdNo tags
FlixBus
Boston (South Station)
1116 Woodruff RdNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Boston to Greenville

Average priceUS$71 - US$234Average duration22h 45m
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average priceUS$216 - US$574Average duration21h 6m
117kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Boston to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 22 hours 45 minutes and with fares starting at just US$71, it presents an excellent value for a comfortable ride.

8bus per day
22h 45mAverage duration
US$71Cheapest ticket
32kgCO₂ emissions

Bus Boston, MA, US to Greenville, SC: Trip Overview

Average ticket priceUS$116
Average bus trip duration22h 45m
Number of daily buses8
Earliest bus departure01:30
Distance795 miles
Latest bus departure22:00

Boston to Greenville Bus

Busbud helps you find a bus from Boston to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Boston to Greenville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Boston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Boston, MA, US - Greenville, SC

  1. How far is Greenville from Boston by coach?

    The journey from Boston to Greenville by coach covers an approximate distance of 801 miles (1291 km).

  2. Is there a way to reach Greenville from Boston without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/10
US$129
11/10
US$145
Today
US$170
13/10
No data
14/10
US$90
15/10
No data
16/10
US$99
17/10
US$104
busbud logoThe cheapest trip from Boston, MA, US to Greenville, SC was searched and found on 14 Oct 2025 with a price of US$90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC as early as possible.

You can expect to pay from US$90 to US$191 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$90, which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Greenville!

Much more than a mere vehicle taking you from Boston to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Boston to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Boston, MA, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Boston, MA, US by bus?

Bus from Greenville, SC to Boston, MA, US

You can also go to Greenville, SC by train

Train from Boston, MA, US to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Boston

Buses Leaving from Boston

Buses Going to Boston

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville