Find the cheapest bus tickets from Florence, SC to Lake City, FL

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Florence to Lake City Buses

Busbud helps you find a bus from Florence to Lake City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Florence to Lake City from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Florence to Lake City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Stations & Stops

For a bus leaving from Florence, the trip starts at Florence Bus Station or TA Travel Center - Florence.

In Lake City, your bus travel ends at Lake City Greyhound Bus Station or Lake City Bus Stop.

Florence to Lake City Route Map

Florence to Lake City Route Map

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Lake City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Lake City, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Lake City that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Florence to Lake City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Florence by bus?

If you are looking for the return bus journey, check out buses from Lake City to Florence.

Popular Buses Connecting Florence

Popular Buses Connecting Lake City

Popular routes in this country

About Busbud

The Best Way To Book Bus Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS, National Express and many others so you can buy tickets without a worry.

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