Bus Tickets from Rochester, NY, US to Chicago

Find affordable bus tickets from Rochester, NY, US to Chicago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 23
TomorrowJun 24
from $86
WedJun 25
from $93
ThuJun 26
FriJun 27
from $105
SatJun 28
from $118
SunJun 29
from $99
MonJun 30
from $118

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 24 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 24 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 24 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 24 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Rochester to Chicago.

Bus
Average Price$62 - $286Average Duration20h 20m
21kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$77 - $197Average Duration11h 43m
76kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Rochester to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 20 hours 20 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.

7bus per day
20h 20mAverage Duration
$62Cheapest ticket
21kgCO₂ emissions

Bus Rochester to Chicago: Trip Overview

Average ticket price$117
Average bus trip duration20h 20m
Number of daily buses6.382352941176472
Earliest bus departure6:10am
Distance518 miles (834 km)
Latest bus departure11:50pm

Rochester to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rochester to Chicago.

We make sure you can find a bus service from Rochester to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Rochester to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Rochester, NY, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/21
$110
06/22
$84
Today
$114
06/24
$105
06/25
$86
06/26
$107
06/27
$129
06/28
$110
busbud logoThe cheapest trip from Rochester to Chicago was searched and found on Jun 22, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester to Chicago, as early as possible.

You can expect to pay from $84 to $188 for a bus ticket from Rochester to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-06-25.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rochester to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rochester to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rochester to Chicago that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Rochester to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester by bus?

Bus from Rochester to Chicago

You can also go to Chicago by train

Train from Rochester to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Rochester

Buses Leaving from Rochester

Buses Going to Rochester

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago