Bus Tickets from Santa Maria, US to Chicago

Previously seen trips

Next departures for Santa Maria to Chicago on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
    		Nicholson Ave
    		Chicago 95Th & Dan RyanNo tags
    Greyhound + FlixBus
      		Nicholson Ave
      		Downtown Greyhound StationNo tags
      FlixBus + Greyhound
        		Nicholson Ave
        		537-517 W. Jackson BlvdNo tags
        Greyhound + FlixBus
          		Nicholson Ave
          		Downtown Greyhound StationNo tags
          FlixBus + Greyhound
            		Nicholson Ave
            		537-517 W. Jackson BlvdNo tags

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            Get from Santa Maria to Chicago

            This route is served by bus only

            The journey takes about 2 days, 12 hours 25 minutes and with fares starting at just $251, it presents an excellent value for a comfortable ride.

            3bus per day
            2d 12hAverage Duration
            1822 milesDistance
            73kgCO₂ emissions

            Bus Santa Maria, US to Chicago: Trip Overview

            Average ticket price$260
            Average bus trip duration2d 12h
            Number of daily buses3
            Earliest bus departure3:15pm
            Distance1822 miles (2938 km)
            Latest bus departure5:25pm

            Santa Maria to Chicago Bus

            With Busbud, comparing and booking tickets for a bus from Santa Maria to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Santa Maria to Chicago from the most reliable bus companies operating this trip.

            Whether it is cheap bus tickets or more luxurious buses going to Chicago from Santa Maria, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions for your trip Santa Maria, US - Chicago

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            10/31
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            11/01
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            Today
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            11/03
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            11/04
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            11/05
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            11/06
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            11/07
            $276
            busbud logoThe cheapest trip from Santa Maria, US to Chicago was searched and found on Nov 7, 2025 with a price of $276

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, US to Chicago, as early as possible.

            You can expect to pay from $276 to $1,403 for a bus ticket from Santa Maria, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $276 which is on 2025-11-07.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Santa Maria to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Maria to Chicago, get comfy and count the stars.

            Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santa Maria to Chicago.

            Make a music playlist for your bus ride from Santa Maria to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            Will you be returning to Santa Maria, US by bus?

            Bus from Chicago to Santa Maria, US

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