Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Lankershim/Magnolia - North Hollywood | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Los Angeles Union Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Downtown LA (Flixbus Lot) | No tags |
Last refresh of the prices: 03/26/2026 EDT.
Compare 2 ways to go from Syracuse to Los Angeles
Among the sustainable travel choices, the Train stands out as a good way to reach Los Angeles. The journey takes about 2 days, 12 hours 52 minutes and with fares starting at just $397, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Los Angeles?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Los Angeles
- A571-581 Gayley Ave, Los Angeles, CA 90024, USA
- B
Ramirez Street bus stop
530 Ramirez St, Los Angeles, CA 90012, USA - C613 Maple Ave, Los Angeles, CA 90014, USA
- E
Downtown Westin Bonaventure
404 S Figueroa St, Los Angeles, CA 90071, USA - F
LAX Airport Holiday Inn
9901 S La Cienega Blvd, Los Angeles, CA 90045, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Syracuse, US to Los Angeles, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Los Angeles?
The cheapest bus tickets from Syracuse to Los Angeles start from $123. The average price for this route is around $261. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Los Angeles?
The average bus trip duration from Syracuse to Los Angeles is 2d 21h, covering a distance of 2329 miles (3756 km). The quickest bus can get you there in 2d 21h and is operated by Greyhound.
Which bus companies service the Syracuse to Los Angeles route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Syracuse to Los Angeles?
The earliest bus departs from Syracuse to Los Angeles at 3:55am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Los Angeles?
A bus trip from Syracuse to Los Angeles generates an estimated 93.890125 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Los Angeles, US was searched and found on Apr 7, 2026 with a price of $219To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Los Angeles, US, as early as possible.
You can expect to pay from $219 to $302 for a bus ticket from Syracuse, US to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $219 which is on 2026-04-07.
What's the cheapest way to go from Syracuse, US to Los Angeles, US?
The Bus is the cheapest travel choice for this destination
