Bus Tickets from St Louis to Lafayette, IN

Find affordable bus tickets from St Louis to Lafayette, IN with flexible options. Book your trip now

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SatJun 28
from US$59
SunJun 29
MonJun 30
TueJul 1
from US$52
WedJul 2
ThuJul 3
FriJul 4
SatJul 5

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: July 2 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: July 1 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: July 1 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: July 1 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 1 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: July 1 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 3:36 PM CDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from St Louis to Lafayette

Bus
Average PriceUS$41 - US$106Average Duration8h 40m
9kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$85 - US$551Average Duration12h 46m
32kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to Lafayette

Among the sustainable travel choices, the bus stands out as a good way to reach Lafayette. The journey takes about 8 hours 40 minutes, and with fares starting at just US$41, it presents an excellent value for a comfortable ride.

3bus per day
8h 40mAverage Duration
US$41Cheapest ticket
9kgCO₂ emissions

Bus St Louis to Lafayette: Trip Overview

Average Ticket PriceUS$56
Average Bus Trip Duration8h 40m
Number of daily buses3
Earliest bus departure2:30am
Distance347 km
Latest bus departure4:00pm

St Louis to Lafayette Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Lafayette.

Bus service from St Louis to Lafayette will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St Louis to Lafayette, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St Louis - Lafayette, IN

  1. What is the travel distance from St Louis to Lafayette?

    It's about 354 km (220 miles) from St Louis to Lafayette.

  2. What are the departure and arrival locations for buses traveling from St Louis to Lafayette?

    Buses departing from Gateway Station in St Louis will take you to CityBus Center in Lafayette.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-24
US$44
06-25
US$50
Today
US$41
06-27
No data
06-28
US$51
06-29
No data
06-30
No data
07-01
US$45
busbud logoThe cheapest trip from St Louis to Lafayette was searched and found on Jun 26, 2025 with a price of US$41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Lafayette, as early as possible.

You can expect to pay from US$41 to US$62 for a bus ticket from St Louis to Lafayette based on the last 2 days. You can expect to find the cheapest price for the trip at US$45 which is on 2025-07-01.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Lafayette but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St Louis to Lafayette, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Lafayette that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from St Louis to Lafayette while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from St Louis to Lafayette?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to Lafayette

You can also go to Lafayette by train

Train from St Louis to Lafayette

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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