Bus Tickets from Charleston, SC, US to Port Saint Lucie

Previously seen trips

Next departures for Charleston to Port Saint Lucie on October 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
4565 Gaynor Ave, North Charleston
Port St Lucie (Park & Ride)No tags
Greyhound + FlixBus
4565 Gaynor Ave, North Charleston
Port St. Lucie (Park & Ride)No tags
FlixBus + Greyhound
4565 Gaynor Ave, North Charleston
Port St. Lucie (Park & Ride)No tags
FlixBus
4565 Gaynor Ave, North Charleston
Port St. Lucie (Park & Ride)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Charleston, SC, US to Port Saint Lucie: Trip Overview

Average ticket price$106
Average bus trip duration12h
Number of daily buses1
Earliest bus departure3:15pm
Distance388 miles (625 km)

Charleston to Port Saint Lucie Bus

With Busbud, comparing and booking tickets for a bus from Charleston to Port Saint Lucie is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Charleston to Port Saint Lucie will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Charleston to Port Saint Lucie, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Charleston, SC, US - Port Saint Lucie

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Charleston to Port Saint Lucie.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Charleston to Port Saint Lucie, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Port Saint Lucie that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Charleston to Port Saint Lucie, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Charleston, SC, US by bus?

Bus from Port Saint Lucie to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Charleston

Buses Leaving from Charleston

Buses Going to Charleston

Popular Buses Connecting Port Saint Lucie

Buses Leaving from Port Saint Lucie

Buses Going to Port Saint Lucie