Bus Tickets from Louisville to Gainesville, FL

Previously seen trips

Next departures for Louisville to Gainesville on October 31
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    Louisville, KY
    Gainesville Bus StopNo tags
    Greyhound
      Louisville, KY
      Gainesville Bus StopNo tags
      FlixBus + Greyhound
        Louisville, KY
        Rosa Parks StationNo tags
        Greyhound + FlixBus
          Louisville, KY
          Gainesville Bus StopNo tags
          Greyhound + FlixBus
            Louisville, KY
            Rosa Parks StationNo tags

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            Get from Louisville to Gainesville

            This route is served by bus only

            The journey takes about 17 hours 40 minutes and with fares starting at just $78, it presents an excellent value for a comfortable ride.

            10bus per day
            17h 40mAverage Duration
            625 milesDistance
            25kgCO₂ emissions

            Bus Louisville to Gainesville, FL: Trip Overview

            Average ticket price$111
            Average bus trip duration17h 40m
            Number of daily buses10
            Earliest bus departure1:35am
            Distance625 miles (1008 km)
            Latest bus departure10:55pm

            Louisville to Gainesville Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Louisville to Gainesville.

            Bus service from Louisville to Gainesville will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to Gainesville from Louisville, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions for your trip Louisville - Gainesville, FL

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            10/29
            $70
            10/30
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            Today
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            11/01
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            11/02
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            busbud logoThe cheapest trip from Louisville to Gainesville, FL was searched and found on Oct 29, 2025 with a price of $70

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Gainesville, FL, as early as possible.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Louisville to Gainesville but it'll also be endearing to native speakers who will surely appreciate your effort.

            Much more than a mere vehicle taking you from Louisville to Gainesville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Gainesville.

            Make a music playlist for your bus ride from Louisville to Gainesville, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            Will you be returning to Louisville by bus?

            Bus from Gainesville, FL to Louisville

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