Bus Tickets from Louisville to San Francisco, US

Previously seen trips

Next departures for Louisville to San Francisco on October 31
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Louisville, KY
San Francisco Bus StationNo tags
Greyhound + FlixBus
Louisville, KY
409 Townsend St, SFNo tags
FlixBus + Greyhound
Louisville, KY
Daly BART - 500 John Daly BlvdNo tags
Greyhound + FlixBus
Louisville, KY
409 Townsend St, SFNo tags
Greyhound
Louisville, KY
San Francisco Bus StationNo tags

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Get from Louisville to San Francisco

busbud logoThis route is served by bus only

The journey takes about 2 days, 11 hours 50 minutes and with fares starting at just $315, it presents an excellent value for a comfortable ride.

4bus per day
2d 11hAverage Duration
1977 milesDistance
80kgCO₂ emissions

Bus Louisville to San Francisco, US: Trip Overview

Average ticket price$389
Average bus trip duration2d 11h
Number of daily buses4
Earliest bus departure8:00am
Distance1976 miles (3187 km)
Latest bus departure10:55pm

Louisville to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from Louisville to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to San Francisco.

From cheap bus tickets to more luxurious buses traveling from Louisville to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Louisville - San Francisco, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/29
$369
10/30
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Today
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11/01
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11/02
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11/03
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11/04
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11/05
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busbud logoThe cheapest trip from Louisville to San Francisco, US was searched and found on Oct 29, 2025 with a price of $369

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to San Francisco, US, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Louisville to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Louisville to San Francisco.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Louisville to San Francisco that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Louisville to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Louisville by bus?

Bus from San Francisco, US to Louisville

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