Compare 2 ways to go from Salisbury to St Louis.
Busbud recommends taking the bus from Salisbury to St LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 19 hours 25 minutes and with fares starting at just $165, it presents an excellent value for a comfortable ride.
Bus Salisbury to St Louis: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Salisbury to St Louis Bus
With Busbud, comparing and booking tickets for a bus from Salisbury to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Salisbury to St Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Salisbury to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Salisbury and St Louis?
Frequently asked questions for your trip Salisbury (NC), US - St Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury to St Louis was searched and found on May 22, 2025 with a price of $232To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury to St Louis, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Salisbury to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Salisbury to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Salisbury to St Louis that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Salisbury to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Salisbury to St Louis?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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