Bus Tickets from Lafayette, LA to St Louis

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TodayJun 21
TomorrowJun 22
from $139
MonJun 23
from $166
TueJun 24
from $173
WedJun 25
from $142
ThuJun 26
from $178
FriJun 27
from $124
SatJun 28
from $152

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 22 at
    Departure city: Lafayette
    Departure location: TA Travel Center - Lafayette
    Arrival time: June 23 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Lafayette
    Departure location: Lafayette Transit System
    Arrival time: June 23 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Lafayette
    Departure location: Lafayette Transit System
    Arrival time: June 23 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Lafayette
    Departure location: Lafayette Transit System
    Arrival time: June 23 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Lafayette
    Departure location: Lafayette Transit System
    Arrival time: June 23 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Accepted payments

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Bus Lafayette to St Louis: Trip Overview

Average ticket price$176
Average bus trip duration1d 3h
Number of daily buses8.153846153846155
Earliest bus departure1:30am
Distance588 miles (948 km)
Latest bus departure10:10pm

Lafayette to St Louis Bus

Busbud helps you find a bus from Lafayette to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Lafayette to St Louis.

Discover how much the bus trip from Lafayette to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Lafayette, LA - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/19
$106
06/20
$124
Today
$165
06/22
$131
06/23
$158
06/24
$166
06/25
$138
06/26
$173
busbud logoThe cheapest trip from Lafayette to St Louis was searched and found on Jun 19, 2025 with a price of $106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette to St Louis, as early as possible.

You can expect to pay from $106 to $214 for a bus ticket from Lafayette to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2025-06-22.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lafayette and St Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Lafayette to St Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lafayette to St Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lafayette to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Lafayette by bus?

Bus from Lafayette to St Louis

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