Compare 2 ways to go from San Diego to Louisville.
Busbud recommends taking the bus from San Diego to LouisvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Louisville. The journey takes about 2 days, 5 hours 20 minutes and with fares starting at just $163, it presents an excellent value for a comfortable ride.
Bus San Diego to Louisville: Trip Overview
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San Diego to Louisville Bus
Busbud helps you find a bus from San Diego to Louisville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Louisville.
From cheap bus tickets to more luxurious buses traveling from San Diego to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Diego and Louisville?
Frequently asked questions for your trip San Diego (CA), US - Louisville
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Louisville was searched and found on Jun 4, 2025 with a price of $220To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Louisville, as early as possible.
You can expect to pay from $220 to $444 for a bus ticket from San Diego to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $220 which is on 2025-06-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Louisville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Louisville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Louisville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from San Diego to Louisville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from San Diego to Louisville?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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