What is the distance between St. Louis and Greenville?

The distance between the two cities is 504 miles (813 km).

What are the departure and arrival stations when taking the bus from St. Louis to Greenville?

If you're headed to Greenville from St. Louis, chances are that your bus will depart from Gateway Station and arrive at Guadalajara Supermarket Bus Stop. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus St. Louis to Greenville from $85 | Refundable Tickets

Previously seen trips

Next departures for St. Louis to Greenville on November 2
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	2:10am	Gateway Station	16h 45m	7:55pm	1116 Woodruff Rd	No tags
FlixBus + Greyhound	2:10am	Gateway Station	16h 45m	7:55pm	1116 Woodruff Rd	No tags
	1:45pm	Gateway Station	16h 50m	7:35am	1116 Woodruff Rd	No tags
	11:15pm	Gateway Station	1d 7h	7:35am	1116 Woodruff Rd	No tags
Greyhound + FlixBus	2:10am	Gateway Station	16h 45m	7:55pm	1116 Woodruff Rd	No tags

Compare 2 ways to go from St. Louis to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 17 hours 40 minutes and with fares starting at just $85, it presents an excellent value for a comfortable ride.

3bus per day

17h 40mAverage Duration

509 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$85 - $228	Average Duration17h 40m	CO₂ emissions 21kg CO₂e
Train	Average Price$246 - $515	Average Duration1d 20h	CO₂ emissions 74kg CO₂e

Bus St. Louis to Greenville, SC: Trip Overview

Average ticket price$132

Average bus trip duration17h 40m

Number of daily buses3

Earliest bus departure1:00am

Distance509 miles (820 km)

Latest bus departure11:30pm

Compare bus companies

FlixBus

3.5/511,153 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,346 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, Sindbad, Infobus, Gontijo, Rider Express

St. Louis to Greenville Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from St. Louis to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from St. Louis, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in St. Louis and Greenville?

Stops in St. Louis

A - Gateway Station

Stops in Greenville

A - Guadalajara Supermarket Bus Stop

B - Greenville Bus Station

Frequently asked questions for your trip St. Louis - Greenville, SC

What is the distance between St. Louis and Greenville?
What are the departure and arrival stations when taking the bus from St. Louis to Greenville?

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from St. Louis to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from St. Louis to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Louis to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from St. Louis to Greenville, SC?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time17h 40m	Avg Price$132	Daily Departures3
Vehicle TypeTrain	Travel Time1d 20h	Avg Price$432	Daily Departures1

Will you be returning to St. Louis by bus?

Bus from Greenville, SC to St. Louis

You can also go to Greenville, SC by train

Train from St. Louis to Greenville, SC

Top traveled bus routes

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The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from St. Louis to Greenville, SC

Previously seen trips

Compare 2 ways to go from St. Louis to Greenville

Bus St. Louis to Greenville, SC: Trip Overview

Compare bus companies

St. Louis to Greenville Bus

Where are the popular stops in St. Louis and Greenville?

Frequently asked questions for your trip St. Louis - Greenville, SC

What is the distance between St. Louis and Greenville?

What are the departure and arrival stations when taking the bus from St. Louis to Greenville?

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from St. Louis to Greenville, SC?

Will you be returning to St. Louis by bus?

You can also go to Greenville, SC by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting St. Louis

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Popular Buses Connecting Greenville

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Popular routes in this country

Popular airport transfers