Bus Tickets from St. Louis to Greenville, SC

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Previously seen trips

One passenger / one way

  • Departure time: September 27 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 27 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 27 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 25 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: October 25 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 25 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: October 25 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from St. Louis to Greenville

Average PriceUS$68 - US$155Average Duration16h 20m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$268 - US$394Average Duration1d 20h
74kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St. Louis to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 16 hours 20 minutes, and with fares starting at just US$68, it presents an excellent value for a comfortable ride.

3bus per day
16h 20mAverage Duration
US$68Cheapest ticket
21kgCO₂ emissions

Bus St. Louis to Greenville, SC: Trip Overview

Average Ticket PriceUS$91
Average Bus Trip Duration16h 20m
Number of daily buses3
Earliest bus departure1:00am
Distance820 km
Latest bus departure11:30pm

St. Louis to Greenville Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from St. Louis to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from St. Louis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St. Louis - Greenville, SC

  1. What is the distance between St. Louis and Greenville?

    St. Louis and Greenville are 813 km (504 miles) apart.

  2. What are the departure and arrival locations for buses traveling from St. Louis to Greenville?

    Buses departing from Gateway Station in St. Louis will take you to Guadalajara Supermarket Bus Stop in Greenville.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from St. Louis to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Louis to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from St. Louis to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Greenville, SC to St. Louis

You can also go to Greenville, SC by train

Train from St. Louis to Greenville, SC

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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