Bus Tickets from Mexico City to San Diego, CA, US

Next departures

Next departures for Mexico City to San Diego on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Mexico City Buenavista (Forum)
San Diego (Old Town-FlixBus)Cheapest
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Mexico City Buenavista (Forum)
UCSD Health La Jolla StationFastest
Flix México + Greyhound Lines Mexico + Valley Transit + Greyhound Lines, Inc.
Mexico City Buenavista (Forum)
Greyhound Bus StopNo tags
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.
Mexico City Buenavista (Forum)
Greyhound Bus StopNo tags
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Mexico City Buenavista (Forum)
Downtown SD (Seaport)No tags

Last refresh of the prices: Yesterday at 5:03 AM CST.

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Bus Mexico City to San Diego, CA, US: Trip Overview

Average ticket price$251
Average bus trip duration2d 20h
Number of daily buses13
Earliest bus departure7:00am
Distance1449 miles (2336 km)
Latest bus departure10:25pm

Mexico City to San Diego Bus

Busbud helps you find a bus from Mexico City to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Mexico City to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Mexico City to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Mexico City - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/07
No data
10/08
$36
Today
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10/10
No data
10/11
No data
10/12
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10/13
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10/14
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busbud logoThe cheapest trip from Mexico City to San Diego, CA, US was searched and found on Oct 8, 2025 with a price of $36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to San Diego, CA, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and San Diego!

Much more than a mere vehicle taking you from Mexico City to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mexico City to San Diego that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexico City to San Diego.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Mexico City by bus?

Bus from San Diego, CA, US to Mexico City

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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