Next departures for San Diego to Boston on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound + FlixBus
Bus
Greyhound Bus Stop
151 Steel Pl, Cambridge
No tags
FlixBus + Greyhound
Bus
5716 Hardy Ave
Boston (South Station)
No tags
Greyhound + FlixBus
Bus
San Diego (Old Town-FlixBus)
Boston (South Station)
No tags
FlixBus + Greyhound
Bus
UCSD Health La Jolla Station
Boston (South Station)
No tags
Bus
Greyhound Bus Stop
Boston (South Station)
No tags
Compare 2 ways to go from San Diego to Boston
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 3 days, 7 hours 35 minutes and with fares starting at just $209, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from San Diego, CA, US to Boston, MA, US by bus
What is the travel distance from San Diego to Boston?
San Diego and Boston are 2576 miles (4155 km) apart.
What are the departure and arrival stations when taking the bus from San Diego to Boston?
The majority of buses traveling from San Diego to Boston start their journey at Mission Valley Sheraton and wind up at Back Bay Station. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Boston?
Once in Boston, you can start exploring the city and discover its surroundings. The top sights and things to do are Boston Fire Museum, JFK Library, Boston Red Sox at Fenway Park, Museum of Science and Boston Celtics at TD Garden.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
No data
11/23
No data
Today
$184
11/25
$198
11/26
No data
11/27
No data
11/28
$167
11/29
No data
The cheapest trip from San Diego, CA, US to Boston, MA, US was searched and found on Nov 28, 2025 with a price of $167
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Boston, MA, US, as early as possible.
You can expect to pay from $167 to $198 for a bus ticket from San Diego, CA, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $167 which is on 2025-11-28.
What's the cheapest way to go from San Diego, CA, US to Boston, MA, US?
The bus is the cheapest travel choice for this destination