What is the travel distance from Santiago to Santa Cruz?

The distance separating Santiago and Santa Cruz is 95 miles (153 km).

What are the departure and arrival stations when taking the bus from Santiago to Santa Cruz?

The majority of buses traveling from Santiago to Santa Cruz start their journey at Terminal Sur and wind up at Terminal Santa Cruz. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

Bus Santiago to Santa Cruz from $7 | Refundable Tickets

Next departures

Next departures for Santiago to Santa Cruz on November 12
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
6:30am	San Bernardo, Santiago (Cruce Colon)	2h 25m	8:55am	Terminal de Buses Santa Cruz	CheapestFastest
9:00am	Terminal Sur	3h	12:00pm	Terminal Santa Cruz	No tags
5:30pm	Terminal Sur	3h 20m	8:50pm	Terminal Santa Cruz	No tags
9:14am	San Bernardo, Santiago (Cruce Colon)	2h 25m	11:39am	Terminal de Buses Santa Cruz	No tags
2:50pm	Terminal Sur	3h	5:50pm	Terminal Santa Cruz	No tags

Next departures for Santiago to Santa Cruz on November 14
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
6:30am	San Bernardo, Santiago (Cruce Colon)	2h 25m	8:55am	Terminal de Buses Santa Cruz	CheapestFastest
3:50pm	Terminal Sur	3h	6:50pm	Terminal Santa Cruz	No tags
7:40am	Terminal Sur	3h 20m	11:00am	Terminal Santa Cruz	No tags
9:14am	San Bernardo, Santiago (Cruce Colon)	2h 25m	11:39am	Terminal de Buses Santa Cruz	No tags
2:50pm	Terminal Sur	3h	5:50pm	Terminal Santa Cruz	No tags

Next departures for Santiago to Santa Cruz on November 15
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
6:30am	San Bernardo, Santiago (Cruce Colon)	2h 25m	8:55am	Terminal de Buses Santa Cruz	CheapestFastest
7:55am	Terminal Sur	3h	10:55am	Terminal Santa Cruz	No tags
7:40am	Terminal Sur	3h 20m	11:00am	Terminal Santa Cruz	No tags
9:14am	San Bernardo, Santiago (Cruce Colon)	2h 25m	11:39am	Terminal de Buses Santa Cruz	No tags
9:00am	Terminal Sur	3h	12:00pm	Terminal Santa Cruz	No tags

Last refresh of the prices: Today at 4:35 PM -03.

Get from Santiago to Santa Cruz

This route is served by bus only

The journey takes about 2 hours 40 minutes and with fares starting at just $4, it presents an excellent value for a comfortable ride.

38bus per day

2h 40mAverage Duration

91 milesDistance

4kgCO₂ emissions

Compare bus companies

Buses Andimar

4/554 reviews

Staff4.4

Timeliness4.6

Cleanliness4.6

Wifi1.2

According to the reviews, customers had a great experience with comfortable bus seats and a very nice conductor. The service was on time as well. However, some passengers mentioned the need for more legroom and discomfort due to another passenger playing videos without headphones throughout the journey.

Andimar Santiago Santa Cruz recent customer reviews

Comfy headrest, but needed more legroom. One passenger played videos without headphones the entire journey 🙄

David H.

March 26, 2024

I won’t use this service again it’s shocking

Jack C.

April 22, 2025

Comfortable seats, very nice conductor, on time !!!

Philip Z.

January 14, 2024

buses TranSantin

4/5276 reviews

Staff4.9

Timeliness4.3

Cleanliness4.5

Wifi1.8

Based on 276 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the wifi. buses TranSantin ticket prices on this trip start at $8

Buses TranSantin Santiago Santa Cruz recent customer reviews

Easy to find. Left on time. Dealt with traffic situations to arrive as soon as practicable.

Paul O.

August 22, 2025

Buses Jet Sur

3.5/577 reviews

Staff4.4

Timeliness4.4

Cleanliness3.9

Wifi0.7

Based on 77 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the ticket access and the departure location but often complained with the wifi. Buses Jet Sur ticket prices on this trip start at $7

Buses Jet Sur Santiago Santa Cruz recent customer reviews

The bus got me to my destination. The seat was uncomfortable, narrow with armrests a bit too high.

Terrence S.

March 21, 2025

Condor Bus

3.5/519 reviews

Pullman Tur

4/572 reviews

Staff4.1

Timeliness4.1

Cleanliness4.4

Wifi2.9

CL bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Santiago and Santa Cruz?

Stops in Santiago

A - Terminal Sur

B - San Borja

C - Terminal Los Héroes

D - Terminal ETM

E - Pajaritos

F - Santiago

Stops in Santa Cruz

A - Terminal Santa Cruz

Frequently asked questions about traveling from Santiago, CL to Santa Cruz, CL by bus

What is the travel distance from Santiago to Santa Cruz?
What are the departure and arrival stations when taking the bus from Santiago to Santa Cruz?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/06

$7

11/07

$8

Today

$7

11/09

$7

11/10

$7

11/11

$7

11/12

$7

11/13

$7

The cheapest trip from Santiago, CL to Santa Cruz, CL was searched and found on Nov 6, 2025 with a price of $7

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Santa Cruz, CL, as early as possible.

You can expect to pay from $7 to $14 for a bus ticket from Santiago, CL to Santa Cruz, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $7 which is on 2025-11-09.

Usually Buses Jet Sur will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

Top traveled bus routes

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