Compare 2 ways to go from St Louis to Gainesville.
Busbud recommends taking the bus from St Louis to GainesvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Gainesville. The journey takes about 21 hours 25 minutes and with fares starting at just $194, it presents an excellent value for a comfortable ride.
Bus St Louis to Gainesville: Trip Overview
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St Louis to Gainesville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Gainesville.
We make it our job to connect you with the most dependable bus companies that cover bus service from St Louis to Gainesville.
From cheap bus tickets to more luxurious buses traveling from St Louis to Gainesville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in St Louis and Gainesville?
Frequently asked questions for your trip St Louis - Gainesville
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to Gainesville was searched and found on May 13, 2025 with a price of $82To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Gainesville, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Gainesville but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from St Louis to Gainesville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Gainesville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from St Louis to Gainesville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from St Louis to Gainesville?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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