Bus Tickets from Wytheville to Panama City, US

Previously seen trips

Next departures for Wytheville to Panama City on October 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Wytheville Bus Station
Panama City Beach StationNo tags
Greyhound
Wytheville Bus Station
Panama City Beach StationNo tags
Greyhound
Wytheville Bus Station
Panama City Beach StationNo tags
Greyhound
Wytheville Bus Station
Panama City Beach StationNo tags
Greyhound
Wytheville Bus Station
Panama City Beach StationNo tags

Accepted payments

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Bus Wytheville to Panama City, US: Trip Overview

Average ticket price$156
Average bus trip duration23h 45m
Number of daily buses2
Earliest bus departure8:50am
Distance546 miles (880 km)
Latest bus departure2:30pm

Wytheville to Panama City Bus

Busbud helps you find a bus from Wytheville to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Wytheville to Panama City will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Wytheville to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Wytheville - Panama City, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/08
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10/09
$146
Today
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10/11
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10/12
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busbud logoThe cheapest trip from Wytheville to Panama City, US was searched and found on Oct 9, 2025 with a price of $146

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wytheville to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wytheville and Panama City!

Much more than a mere vehicle taking you from Wytheville to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wytheville to Panama City that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Wytheville to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Wytheville by bus?

Bus from Panama City, US to Wytheville

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