Bus Tickets from Columbus, OH to St Louis, MO

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TodayMay 7
from US$71
TomorrowMay 8
FriMay 9
SatMay 10
SunMay 11
MonMay 12
TueMay 13
WedMay 14

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 7 at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: May 8 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 7 at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: May 8 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 7:28 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Columbus to St Louis: Trip Overview

Average Ticket PriceUS$73
Average Bus Trip Duration11h 30m
Number of daily buses5
Earliest bus departure4:50am
Distance637 km
Latest bus departure11:30pm

Columbus to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbus to St Louis.

Bus service from Columbus to St Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbus to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus - St Louis

  1. How long is the bus trip from Columbus to St Louis?

    The bus ride from Columbus to St Louis takes 11h 30m, on average. The fastest bus on this trip will get to St Louis in 9h 20m

  2. How far is Columbus from St Louis?

    The distance between Columbus and St Louis is around 638 km (396 miles).

  3. What are the departure and arrival locations for buses traveling from Columbus to St Louis?

    Buses traveling this route start their trip at Columbus Bus Station, in Columbus, and end it at Gateway Station, in St Louis.

  4. What is the cheapest way to travel from Columbus to St Louis?

    Taking the bus is the cheapest option to travel from Columbus to St Louis. Starting at US$59, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Columbus to St Louis?

    Taking the bus from Columbus to St Louis costs on average US$73.

  6. Can I take an overnight bus from Columbus to St Louis?

    Yes! Catch buses leaving from Columbus until 11:30pm and reaching St Louis on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-05
US$59
05-06
No data
Today
US$59
05-08
US$51
05-09
No data
05-10
No data
05-11
No data
05-12
No data
busbud logoThe cheapest trip from Columbus to St Louis was searched and found on May 8, 2025 with a price of US$51

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to St Louis, as early as possible.

You can expect to pay from US$51 to US$124 for a bus ticket from Columbus to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$51 which is on 2025-05-08.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbus to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Columbus to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbus to St Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Columbus to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Columbus by bus?

Bus from Columbus to St Louis

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