Bus Tickets from Des Moines to Greenville (SC)

Taking the bus is the best way to travel to Greenville without flying. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. You also have the choice of using carpooling services.

On average, the trip from Des Moines to Greenville takes around 1d 5h, but you can get there in as little as 1d 5h with the fastest bus. This is the time it takes to travel the 765 miles (1234 km) that separate the two cities.

The distance separating Des Moines and Greenville is 765 miles (1234 km).

If you're headed to Greenville from Des Moines, chances are that your bus will leave from Jefferson/Trailways Depot and arrive at Guadalajara Supermarket Bus Stop. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

Go for the bus if you want the most cost-effective way to travel this route. With prices starting at $155, you won't find a cheaper way to get there.

You can expect to pay around $155 for a bus ticket. Over the last 30 days, the prices ranged between $155 and $157, so make sure to compare them to get the best option.

Certainly! You can indeed opt for an overnight bus from Des Moines to Greenville. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.