Is there a way to reach St Louis from San Antonio without flying?

You have the option of traveling from one city to the other by either bus or train. Either way you choose, you'll be sure to reach your destination in the most easy and sustainable way. You can also use carpool services and share a car ride with other travelers.

How long does it take to get to St Louis from San Antonio by bus?

The travel time from San Antonio to St Louis is about 1d, although the minimum time it takes to get there is 20h 40m with the fastest bus. This is the time it takes to travel the 793 miles (1278 km) that separate the two cities.

What is the distance between San Antonio and St Louis?

About 793 miles (1278 km) separate San Antonio and St Louis.

What are the departure and arrival stations when taking the bus from San Antonio to St Louis?

If you're headed to St Louis from San Antonio, chances are that your bus will leave from San Antonio Bus Station and arrive at Gateway Station. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What is the most cost-effective way to go from San Antonio to St Louis?

Go for the bus if you want the most economical way to travel this route. $102 is the starting point for the cost-effective bus ride to St Louis from San Antonio.

What is the ticket price for the bus trip from San Antonio to St Louis?

The average price of a one-way ticket from San Antonio to St Louis is $138. Over the last 30 days, the prices ranged between $102 and $308, so make sure to compare them to get the best option.

What are the best sights and things to do in St Louis?

Once in St Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Scott Joplin House State Historic Site, Gateway Arch, Forest Park, St. Louis Cardinals and Lumière Place.

Is it possible to travel by overnight bus from San Antonio to St Louis?

Yes, you can take a night bus to go from San Antonio to St Louis. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.

San Antonio (TX), US to St Louis Bus Tickets

TodayMay 28

TomorrowMay 29

from $130

FriMay 30

SatMay 31

SunJun 1

MonJun 2

TueJun 3

WedJun 4

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: May 29 at 9:00pm
Departure city: San Antonio
Departure location: San Antonio Bus Station
Arrival time: May 30 at 10:10pm
Destination city: St Louis
Destination location: St Louis, MO
Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc.
Valley Transit Co., Inc. + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 1h
This trip is recommended because it is: Fastest
Departure time: May 29 at 1:30am
Departure city: San Antonio
Departure location: San Antonio Bus Station
Arrival time: May 29 at 10:10pm
Destination city: St Louis
Destination location: St Louis, MO
Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
Greyhound Lines Mexico + Greyhound Lines, Inc.
Vehicle: BusDuration: 20h 40m
Departure time: May 29 at 1:30am
Departure city: San Antonio
Departure location: San Antonio Bus Station
Arrival time: May 29 at 10:40pm
Destination city: St Louis
Destination location: Gateway Station
Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
Greyhound Lines Mexico + Greyhound Lines, Inc.
Vehicle: BusDuration: 21h 10m
Departure time: May 29 at 12:40pm
Departure city: San Antonio
Departure location: San Antonio Bus Station
Arrival time: May 30 at 12:55pm
Destination city: St Louis
Destination location: Gateway Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d
Departure time: May 29 at 9:00pm
Departure city: San Antonio
Departure location: San Antonio Bus Station
Arrival time: May 30 at 10:40pm
Destination city: St Louis
Destination location: Gateway Station
Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc.
Valley Transit Co., Inc. + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 1h

Accepted payments

Compare 2 ways to go from San Antonio to St Louis.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$102 - $308	Average Duration1d	CO₂ emissions 32kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$112 - $333	Average Duration1d 2h	CO₂ emissions 116kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from San Antonio to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 1 day, 15 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.

4bus per day

1d Average Duration

$102Cheapest ticket

32kgCO₂ emissions

Bus San Antonio to St Louis: Trip Overview

Average ticket price$138

Average bus trip duration1d

Number of daily buses4

Earliest bus departure1:30am

Distance791 miles (1275 km)

Latest bus departure9:45pm

Compare bus companies

Greyhound

3.5/587,006 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Valley Transit

3.5/521 reviews

Staff4.4

Timeliness4.4

Cleanliness4.1

Wifi2.8

FlixBus

3.5/58,806 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

San Antonio to St Louis Bus

Busbud helps you find a bus from San Antonio to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Antonio to St Louis.

Discover how much the bus trip from San Antonio to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in San Antonio and St Louis?

Stops in San Antonio

A - San Antonio Bus Station

B - Tornado I-35

C - San Antonio, TX

D - 4407 S PanAm Expy #101

Stops in St Louis

A - Gateway Station

Frequently asked questions for your trip San Antonio (TX), US - St Louis

Is there a way to reach St Louis from San Antonio without flying?
How long does it take to get to St Louis from San Antonio by bus?
What is the distance between San Antonio and St Louis?
What are the departure and arrival stations when taking the bus from San Antonio to St Louis?
What is the most cost-effective way to go from San Antonio to St Louis?
What is the ticket price for the bus trip from San Antonio to St Louis?
What are the best sights and things to do in St Louis?
Is it possible to travel by overnight bus from San Antonio to St Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/26

$148

05/27

$160

Today

No data

05/29

$140

05/30

$158

05/31

$172

06/01

$101

06/02

$161

The cheapest trip from San Antonio to St Louis was searched and found on Jun 1, 2025 with a price of $101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to St Louis, as early as possible.

You can expect to pay from $101 to $172 for a bus ticket from San Antonio to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $101 which is on 2025-06-01.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Antonio and St Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Antonio to St Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to St Louis will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Antonio to St Louis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from San Antonio to St Louis?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d	Avg Price$138	Daily Departures4
Vehicle TypeTrain	Travel Time1d 2h	Avg Price$182	Daily Departures1

Will you be returning to San Antonio by bus?

Bus from San Antonio to St Louis

You can also go to St Louis by train

Train from San Antonio to St Louis

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from San Antonio (TX), US to St Louis