Compare 2 ways to go from St Louis to Portland.
Busbud recommends taking the train from St Louis to PortlandAmong the sustainable travel choices, the train stands out as the good way to reach Portland. The journey takes about 2 days, 8 hours 47 minutes and with fares starting at just $325, it presents an excellent value for a comfortable ride.
Bus St Louis to Portland: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
St Louis to Portland Bus
Busbud helps you find a bus from St Louis to Portland. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from St Louis to Portland will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from St Louis to Portland, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in St Louis and Portland?
Frequently asked questions for your trip St Louis - Portland
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to Portland was searched and found on May 3, 2025 with a price of $381To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Portland, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St Louis and Portland!
Much more than a mere vehicle taking you from St Louis to Portland, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Portland that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St Louis to Portland.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.