Next departures to St. Louis
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: August 19 atDeparture city: PortlandDeparture location: Portland Curbside Bus StopArrival time: August 21 atDestination city: St. LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: August 19 atDeparture city: PortlandDeparture location: PDX AirportArrival time: August 22 atDestination city: St. LouisDestination location: Gateway StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: August 19 atDeparture city: PortlandDeparture location: Portland Curbside Bus StopArrival time: August 21 atDestination city: St. LouisDestination location: Saint Louis (Lambert Field)Operated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: August 19 atDeparture city: PortlandDeparture location: PDX AirportArrival time: August 22 atDestination city: St. LouisDestination location: Gateway StationOperated by: AmtrakVehicle: BusDuration:
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Bus Portland, OR to St. Louis: Trip Overview
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Portland to St. Louis Bus
With Busbud, comparing and booking tickets for a bus from Portland to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Portland to St. Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Portland to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Portland and St. Louis?
Frequently asked questions for your trip Portland, OR - St. Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, OR to St. Louis was searched and found on Aug 18, 2025 with a price of $129To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to St. Louis, as early as possible.
You can expect to pay from $129 to $2,441 for a bus ticket from Portland, OR to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $129 which is on 2025-08-18.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Portland to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Portland to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to St. Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Portland to St. Louis while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.