Next departures for Buffalo to Philadelphia on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
CheapestFastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
New York Trailways + Peter Pan
Bus
Transportation Center
12 Schuylkill Ave
No tags
Next departures for Buffalo to Philadelphia on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
Cheapest
Bus
Buffalo Niagara International Airport, (Arrivals) Bus parking area
12 Schuylkill Ave
Fastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
Next departures for Buffalo to Philadelphia on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
Cheapest
Bus
Buffalo Niagara International Airport, (Arrivals) Bus parking area
12 Schuylkill Ave
Fastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
Next departures for Buffalo to Philadelphia on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
CheapestFastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
No tags
Next departures for Buffalo to Philadelphia on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
CheapestFastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
No tags
Next departures for Buffalo to Philadelphia on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
CheapestFastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
No tags
Next departures for Buffalo to Philadelphia on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
Cheapest
Bus
Buffalo Niagara International Airport, (Arrivals) Bus parking area
12 Schuylkill Ave
Fastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
Next departures for Buffalo to Philadelphia on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Transportation Center
Philadelphia (Spring Garden)
Cheapest
Bus
Buffalo Niagara International Airport, (Arrivals) Bus parking area
12 Schuylkill Ave
Fastest
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
199 Spring Garden St.
No tags
Bus
Niagara Frontier Transportation Authority
Philadelphia, 199 Spring Garden St
No tags
Last refresh of the prices: Today at 3:47 AM EST.
Compare 2 ways to go from Buffalo to Philadelphia
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Philadelphia. The journey takes about 12 hours 16 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Buffalo Philadelphia recent customer reviews
With about 2 daily trips between Buffalo and Philadelphia, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Fullington offers 1 daily departures, and you can find tickets starting at $143. The quickest ride takes around 1410. Fullington offers a cost-effective solution to get you where you need to be.
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Frequently asked questions about traveling from Buffalo, NY to Philadelphia, PA by bus
What is the travel distance from Buffalo to Philadelphia?
Buffalo and Philadelphia are 280 miles (451 km) apart.
What are the departure and arrival stations when taking the bus from Buffalo to Philadelphia?
The majority of buses traveling from Buffalo to Philadelphia start their journey at Buffalo Airport and wind up at Philadelphia Airport. These are the most popular departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Love Park, Reading Terminal Market, Please Touch Museum, Shofuso Japanese House and Garden and National Museum of Jewish History.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$120
11/21
$141
Today
$118
11/23
$105
11/24
$110
11/25
$148
11/26
$156
11/27
$99
The cheapest trip from Buffalo, NY to Philadelphia, PA was searched and found on Nov 27, 2025 with a price of $99
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Philadelphia, PA, as early as possible.
You can expect to pay from $99 to $312 for a bus ticket from Buffalo, NY to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $99 which is on 2025-11-27.
Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Buffalo, NY to Philadelphia, PA?
The bus is the cheapest travel choice for this destination