Bus Tickets from Syracuse, US to St Louis

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TodayJun 28
TomorrowJun 29
MonJun 30
from $126
TueJul 1
from $118
WedJul 2
ThuJul 3
FriJul 4
SatJul 5

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 30 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: July 1 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 30 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: July 1 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Syracuse to St Louis.

Bus
Average Price$66 - $257Average Duration1d 3h
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$112 - $1,023Average Duration22h 2m
116kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Syracuse to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 1 day, 3 hours 35 minutes and with fares starting at just $66, it presents an excellent value for a comfortable ride.

2bus per day
1d 3hAverage Duration
$66Cheapest ticket
32kgCO₂ emissions

Bus Syracuse to St Louis: Trip Overview

Average ticket price$141
Average bus trip duration1d 3h
Number of daily buses2
Earliest bus departure4:30am
Distance793 miles (1278 km)
Latest bus departure9:00pm

Syracuse to St Louis Bus

With Busbud, comparing and booking tickets for a bus from Syracuse to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Syracuse to St Louis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Syracuse to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Syracuse, US - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/26
$90
06/27
No data
Today
$112
06/29
No data
06/30
$118
07/01
$110
07/02
No data
07/03
$59
busbud logoThe cheapest trip from Syracuse to St Louis was searched and found on Jul 3, 2025 with a price of $59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to St Louis, as early as possible.

You can expect to pay from $59 to $163 for a bus ticket from Syracuse to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-07-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Syracuse to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to St Louis, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Syracuse to St Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Syracuse to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Syracuse to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse by bus?

Bus from Syracuse to St Louis

You can also go to St Louis by train

Train from Syracuse to St Louis

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