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| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Key West Bus Station | Knoxville Bus Station | No tags |
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Get from Key West to Knoxville
The journey takes about 1 day, 4 hours 50 minutes and with fares starting at just $180, it presents an excellent value for a comfortable ride.
Bus Key West to Knoxville, TN: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Key West to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Key West to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Key West to Knoxville.
From cheap bus tickets to more luxurious buses traveling from Key West to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Key West and Knoxville?
Frequently asked questions for your trip Key West - Knoxville, TN
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Key West to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Key West to Knoxville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Key West to Knoxville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Key West to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top traveled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Key West
Buses Leaving from Key West
- Bus from Key West to Miami
- Bus Key West - Key Largo
- Key West - Tampa
- Bus from Key West to Fort Lauderdale
- Bus Key West - Islamorada
- Key West - Fort Myers
- Bus from Key West to Orlando
- Bus Key West - Marathon
- Key West - Daytona Beach
- Bus from Key West to Jacksonville
- Bus Key West - Atlanta
- Key West - West Palm Beach
- Bus from Key West to Big Pine Key
- Bus Key West - Sarasota
- Key West - New York City
Buses Going to Key West
- Bus from Orlando to Key West
- Bus Tampa - Key West
- Key Largo - Key West
- Bus from Islamorada to Key West
- Bus Marathon - Key West
- Miami - Key West
- Bus from Fort Lauderdale to Key West
- Bus West Palm Beach - Key West
- St. Petersburg - Key West
- Bus from Boynton Beach to Key West
- Bus Jupiter - Key West
- Jacksonville - Key West
- Bus from Sarasota to Key West
- Bus New York City - Key West
- Perry - Key West
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Tampa
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Hartford - Knoxville
- New York City - Knoxville
- Bus from Louisville to Knoxville
- Bus Cincinnati - Knoxville
- Lexington - Knoxville
- Bus from Greenville to Knoxville
- Bus Dallas - Knoxville
- Cookeville - Knoxville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio