Bus Tickets from San Antonio, US to Knoxville, TN

Previously seen trips

Next departures for San Antonio to Knoxville on November 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		San Antonio Bus Station
    		Knoxville Bus StationNo tags
    Greyhound
      		San Antonio Bus Station
      		Knoxville Bus StationNo tags
      Greyhound + Valley Transit
        		San Antonio Bus Station
        		Knoxville Bus StationNo tags
        Valley Transit + Greyhound
          		San Antonio Bus Station
          		Knoxville Bus StationNo tags
          Greyhound
            		San Antonio Bus Station
            		Knoxville Bus StationNo tags

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            Get from San Antonio to Knoxville

            This route is served by bus only

            The journey takes about 1 day, 2 hours 25 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.

            2bus per day
            1d 2hAverage Duration
            960 milesDistance
            39kgCO₂ emissions

            Bus San Antonio, US to Knoxville, TN: Trip Overview

            Average ticket price$114
            Average bus trip duration1d 2h
            Number of daily buses2
            Earliest bus departure1:30pm
            Distance960 miles (1548 km)
            Latest bus departure9:15pm

            San Antonio to Knoxville Bus

            With Busbud, comparing and booking tickets for a bus from San Antonio to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from San Antonio to Knoxville will be provided by the most trusted bus companies.

            Discover how much the bus trip from San Antonio to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions for your trip San Antonio, US - Knoxville, TN

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/03
            $123
            11/04
            $91
            Today
            $93
            11/06
            No data
            11/07
            $110
            11/08
            No data
            11/09
            No data
            11/10
            No data
            busbud logoThe cheapest trip from San Antonio, US to Knoxville, TN was searched and found on Nov 4, 2025 with a price of $91

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Knoxville, TN, as early as possible.

            You can expect to pay from $91 to $123 for a bus ticket from San Antonio, US to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-11-07.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from San Antonio to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from San Antonio to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to Knoxville will emit less CO2 than a car or an airplane.

            Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to Knoxville while indulging in miles on end of beautiful scenic views.

            Did you know?

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            Will you be returning to San Antonio, US by bus?

            Bus from Knoxville, TN to San Antonio, US

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