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| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | 4565 Gaynor Ave, North Charleston | Knoxville Bus Station | No tags | |||||
| 4565 Gaynor Ave, North Charleston | Knoxville Bus Station | No tags | |||||
| 4565 Gaynor Ave, North Charleston | Knoxville Bus Station | No tags | |||||
| 4565 Gaynor Ave, North Charleston | 100 Kirkwood St | No tags | |||||
FlixBus + Greyhound | 4565 Gaynor Ave, North Charleston | Knoxville Bus Station | No tags |
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Get from Charleston to Knoxville
The journey takes about 1 day, 7 hours 55 minutes and with fares starting at just $205, it presents an excellent value for a comfortable ride.
Bus Charleston, SC, US to Knoxville, TN: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Charleston to Knoxville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Charleston to Knoxville.
We make it our job to connect you with the most dependable bus companies that cover bus service from Charleston to Knoxville.
Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Charleston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Charleston and Knoxville?
Frequently asked questions for your trip Charleston, SC, US - Knoxville, TN
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Charleston to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Charleston to Knoxville.
Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to Knoxville.
Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to Knoxville while indulging in miles on end of beautiful scenic views.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
- Bus Charleston - Atlanta
- Charleston - Tulsa
- Bus from Charleston to Fort Worth
- Bus Charleston - Miami
- Charleston - Jacksonville
- Bus from Charleston to Savannah
- Bus Charleston - Greenville
- Charleston - Charlotte
- Bus from Charleston to Orlando
- Bus Charleston - New York City
- Charleston - Raleigh
- Bus from Charleston to Florence
- Bus Charleston - Greensboro
- Charleston - Washington
Buses Going to Charleston
- Bus from Myrtle Beach to Charleston
- Bus Baltimore - Charleston
- Boston - Charleston
- Bus from Greenville to Charleston
- Bus Nashville - Charleston
- Raleigh - Charleston
- Bus from Savannah to Charleston
- Bus Atlanta - Charleston
- Orlando - Charleston
- Bus from New York City to Charleston
- Bus Charlotte - Charleston
- Miami - Charleston
- Bus from Jacksonville to Charleston
- Bus Tampa - Charleston
- Newark - Charleston
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Tampa
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Hartford - Knoxville
- New York City - Knoxville
- Bus from Louisville to Knoxville
- Bus Cincinnati - Knoxville
- Lexington - Knoxville
- Bus from Greenville to Knoxville
- Bus Dallas - Knoxville
- Cookeville - Knoxville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio