Find cheap bus tickets from Fort Myers to San Francisco

Easily compare and book your next trip with Busbud

Trusted by 65M+ travelers every year looking for bus and train tickets
Serving 2M+ bus and train routes in more than 80 countries
Dedicated customer service from booking to travel
TodayApr 26
TomorrowApr 27
SunApr 28
MonApr 29
TueApr 30
WedMay 1
from $222
ThuMay 2
FriMay 3

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 1 at
    Departure city: Fort Myers
    Departure location: Daniels Pkwy & I-75
    Arrival time: May 5 at
    Destination city: San Francisco
    Destination location: Salesforce Transit Center
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $257
  • This trip is recommended because it is: 2nd Cheapest
    Departure time: May 1 at
    Departure city: Fort Myers
    Departure location: Love's Travel Stop
    Arrival time: May 5 at
    Destination city: San Francisco
    Destination location: San Francisco, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
    $623
  • Departure time: May 1 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: May 4 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $222
  • Departure time: May 1 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: May 4 at
    Destination city: San Francisco
    Destination location: Salesforce Transit Center
    Operated by
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $222
  • Departure time: May 1 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: May 4 at
    Destination city: San Francisco
    Destination location: Hyde/Beach (Fisherman's Wharf)
    Operated by
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $223
Bus Fort Myers to San Francisco: Trip Overview

Bus Fort Myers to San Francisco: Trip Overview

Average ticket price$283
Average bus trip duration3d 13h
Number of daily buses10
Earliest bus departure7:00 AM
Distance2465 miles (3975 km)
Latest bus departure8:20 PM

Fort Myers to San Francisco Buses

Information on this bus route

Daily Departures10
Earliest and Latest Bus Departures7:00AM - 8:20PM
Minimum Price$261
Average Ticket Price$283
Minimum Trip Duration3d6h
Average Bus Trip Duration3d13h
Distance2465 miles (3975 km)
Bus Companies on This RouteFlixBus, Greyhound
Frequently Asked Questions

Frequently asked questions for your trip Fort Myers - San Francisco

The bus is the best choice to get to San Francisco without flying. The bus provides a cost-effective, safe, and easy way to travel between the two cities. You also have the choice of using carpooling services.

Traveling from Fort Myers to San Francisco takes around 3d 13h on average, but you can get there in as little as 3d 6h with the fastest bus. This is the time it takes to travel the 2471 miles (3984 km) that separate the two cities.

About 2471 miles (3984 km) separate Fort Myers and San Francisco.

You can choose from 10 travel times and travel with FlixBus and Greyhound. Depending on the day of the week, the number of buses available from Fort Myers to San Francisco may vary. Busbud can make your trip from Fort Myers to San Francisco a breeze! Simply check the schedules and pick the bus that matches your needs and budget. It's that easy!

The bus service has you covered with departures starting at 7:00 AM and ending at 8:20 PM.

Most of the buses traveling from Fort Myers to San Francisco leave from Daniels Pkwy & I-75 and arrive at Hyde/Beach (Fisherman's Wharf). These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

If you want the cheapest way to travel this route, choose the bus. The lowest tickets for this trip cost as little as $261.

The average price of a one-way ticket from Fort Myers to San Francisco is $283. In the past 30 days, prices have fluctuated between $261 and $647, so it's best to compare them to make sure you get the best deal.

Once in San Francisco, you can start exploring the city and discover its surroundings. The top sights and things to do are Lombard Street, Ocean Beach, Cable Car Museum, Fisherman’s Wharf and Walt Disney Family Museum.

Yes, you can take a night bus to go from Fort Myers to San Francisco. Remember to bring along essentials like a blanket and some snacks to ensure a cozy and convenient journey.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Fort Myers and San Francisco!

Much more than a mere vehicle taking you from Fort Myers to San Francisco, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Fort Myers to San Francisco will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Fort Myers to San Francisco.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Fort Myers by bus?

Bus from San Francisco to Fort Myers

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.